As a freshman, he appeared in 11 games, playing as an offensive tackle or tight end. He had his lone reception, a 22-yard touchdown, in the 54–36 win against Purdue University, which sealed a bowl berth. He was named honorable-mention BTN.com All-Freshman.[1]
As a sophomore, he appeared in the first 8 games, starting six at right tackle after fifth-year senior Dimitric Camiel had back surgery. He suffered a season-ending left leg injury against the University of Maryland.[1]
As a junior, an unspecified injury kept him out of the early season games, but was able to return to play in the final 10 contests with 8 starts at right tackle.[1]
As a senior, he started all 12 games at right tackle, allowing three sacks in 904 snaps. He received honorable-mention All-Big Ten honors at the end of the season. He finished with 41 career and 26 starts at right tackle.
In 2020, reserve swing tackle Cameron Fleming was not re-signed, opening the door for Knight to become the backup at left tackle. After starter Tyron Smith was placed on the injured reserve list due to a neck surgery, the Cowboys announced that Knight would fill in as the replacement. He underwent a knee scope after Week 6 and was placed on injured reserve on October 24, 2020.[5] He was activated on November 21, 2020.[6] He appeared in 13 games with 9 starts at left tackle.
In 2021, he was mostly a reserve offensive tackle, playing only 3 snaps in one game. On October 16, 2021, Knight was waived by the Cowboys.[7]
Baltimore Ravens
On October 18, 2021, Knight was claimed off waivers by the Baltimore Ravens.[8] He was acquired to provide depth on the offensive line while Ronnie Stanley recovered from an ankle injury. On October 21, 2021, Knight announced that he elected not to join the team, in order to focus on his mental health. The Ravens placed him on the reserve/did not report list to keep his player rights.[9]