Befloxatone

Befloxatone
Names
Preferred IUPAC name
(5R)-5-(Methoxymethyl)-3-{4-[(3R)-4,4,4-trifluoro-3-hydroxybutoxy]phenyl}-1,3-oxazolidin-2-one
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
  • InChI=1S/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1 checkY
    Key: IALVDLPLCLFBCF-CHWSQXEVSA-N checkY
  • InChI=1/C15H18F3NO5/c1-22-9-12-8-19(14(21)24-12)10-2-4-11(5-3-10)23-7-6-13(20)15(16,17)18/h2-5,12-13,20H,6-9H2,1H3/t12-,13-/m1/s1
    Key: IALVDLPLCLFBCF-CHWSQXEVBB
  • O=C2O[C@H](CN2c1ccc(OCC[C@@H](O)C(F)(F)F)cc1)COC
Properties
C15H18F3NO5
Molar mass 349.30233
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Befloxatone (MD-370,503) is a reversible inhibitor of monoamine oxidase A.[1][2]

References

  1. ^ Emilien, G (March 1999). "Befloxatone (Synthelabo)". IDrugs. 2 (3): 247–253. PMID 16160936.
  2. ^ Warot, Dominique; Berlin, Ivan; Patat, Alain; Durrieu, Geneviève; Zieleniuk, Isabelle; Puech, Alain J (October 1996). "Effects of Befloxatone, a Reversible Selective Monoamine Oxidase-A Inhibitor, on Psychomotor Function and Memory in Healthy Subjects". The Journal of Clinical Pharmacology. 1552-4604. 36 (10): 942–950. doi:10.1002/j.1552-4604.1996.tb04762.x. PMID 8930782. S2CID 36177710.


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