Asael Lubotzky

Asael Lubotzky
Born1983
Jerusalem, Israel
Education
Known for
RelativesProfessor Alex Lubotzky (father)
Medical career
ProfessionPediatrician, researcher, writer
InstitutionsHebrew University of Jerusalem
Shaare Zedek Medical Center
Hospital for Sick Children (Toronto)
ResearchEpigenetics, Cell-free DNA
Awards
From the Wilderness and Lebanon

Asael Lubotzky (Hebrew: עשהאל לובוצקי; born 21 January 1983) is an Israeli physician, author, and molecular biologist. Formerly an officer in the Israel Defense Forces (IDF), he is a combat veteran of the Second Lebanon War.

Military service

Asael Lubotzky grew up in Efrat, studied at the Hesder yeshiva in Ma'ale Adumim, was accepted to Shayetet 13, but chose to enlist in Golani's 51st Battalion. He underwent a training course as a combat soldier and was chosen as the outstanding company cadet. After completing Officer Candidate School Asael served as an officer commanding a platoon of the Golani Brigade. He led his platoon in operations in Gaza and, during the Second Lebanon War, fought in many battles in which many of his comrades were killed and wounded, until his own severe injury in the Battle of Bint Jbeil[1] left him with a disability.[2][3]

Medical and research career

Following his rehabilitation, Lubotzky pursued a medical degree at the Hebrew University Hadassah Medical School,[4] qualified as a doctor,[5] and specialized in pediatrics at the Shaare Zedek Hospital in Jerusalem.[6] and continued to a Neurology Fellowship. Additionally, Lubotzky completed a fellowship in Neonatal Neurology at The Hospital for Sick Children (SickKids) in Toronto, Canada.[7]

Lubotzky conducted research in the lab of professor Haim Cedar and became a PhD student under Professor Yuval Dor and Ruth Shemer at the Hebrew University's Department of Developmental Biology and Cancer Research, who works on methylation patterns of circulating cell-free DNA (cfDNA). Lubotzky was recognized for his studies on cfDNA as cancer diagnostic markers, and his research has earned him several honors, including the Israel Cancer Research Fund (ICRF) cancer grant[8][9] and in 2019, he was awarded The James Sivartsen Prize in Cancer Research by The Hebrew University.[10]

In 2020 his research team received a prestigious grant of $500,000 from the Bill & Melinda Gates Foundation and Alzheimer's Drug Discovery Foundation towards their research on early diagnosis of Alzheimer's disease based on blood tests.[11]

In 2021 he received the Joint Award of the National Institute of Psychobiology in Israel (NIPI) and the Israeli Society of Biological Psychiatry.[12]

In 2021 he was awarded a PhD for a thesis entitled: "Liquid Biopsies Reveal Collateral Tissue Damage in Cancer and Brain Damage in Neural Pathologies".[13] His findings demonstrated that metastatic tumors cause collateral tissue damage, releasing cfDNA from affected organs, and that cfDNA methylation patterns can help pinpoint metastases and their tissue origins.[14]

In 2022 he received The Rothschild Fellowship for young scholars of outstanding academic merit.[15] In the same year, Lubotzky and his colleagues published a study showing that brain cells die during psychotic episodes, with higher levels of brain-derived cfDNA detected in patients experiencing psychotic symptoms, compared to healthy controls.[16] The finding would serve as a proof of concept for brain-derived cell-free DNA as biomarkers of psychosis.[17]

In 2023, Lubotzky received the Ben Barres Spotlight Award by eLife for his research towards understanding brain dynamics.[18]

Writing

Lubotzky's first book, From the Wilderness and Lebanon, recounting his wartime experiences and rehabilitation, was published in 2008 by Yedioth Ahronoth, The book became a best-seller, received critical acclaim[19] and was translated into English.[20] His second book, Not My Last Journey, which chronicles the life story of his grandfather, the partisan and Irgun officer Iser Lubotzky, was published in Hebrew in 2017 by Yedioth Books and Menachem Begin Heritage Center.[21]

Lubotzky won the Leitersdorf Prize for the Arts for 2017.[22] Lubotzky lectures on various topics in Israel and internationally.[23][24][25]

Personal life

Asael Lubotzky is the son of Alex Lubotzky and grandson of Murray Roston. He lives in Jerusalem, is married to Avital (Schimmel), a medical psychologist and they have six children.[26][27]

Books

  • מן המדבר והלבנון‎ (Min HaMidbar VeHaLevanon), Yedioth Ahronoth, 2008
  • From the Wilderness and Lebanon, The Toby Press, Koren Publishers Jerusalem, 2016. English translation of the previous book by Professor Murray Roston
  • לא דרכי האחרונה‎ (Not My Last Journey), Yedioth Ahronoth & Menachem Begin Heritage Center, 2017

References

  1. ^ BBC - Dr. Asael Lubotzky Reflects on the 2006 Lebanon War, BBC Newshour, September 25, 2024.
  2. ^ Magnezi, Aviel (December 14, 2010). "War veteran returns to hospital as doctor: Golani Brigade officer Asael Lubotzky, who was critically injured during Second Lebanon War". Ynetnews.
  3. ^ This is Israel: Resilience. February 14, 2013 – via YouTube, Aish HaTorah.
  4. ^ The Battle of His Life: Asael Lubotzky's Story. June 5, 2012 – via YouTube, Rambam Health Care Campus.
  5. ^ Elizera, Rotem (July 3, 2015). "From wounded hero to pediatrician". Ynetnews.
  6. ^ The Hero Healer Archived 2018-02-19 at the Wayback Machine, Noga Tarnopolsky, Jewish News, September 29, 2016.
  7. ^ Dr. Asael Lubotzky, American Healthcare Professionals and Friends for Medicine in Israel
  8. ^ Hebrew U receives major portion of ICRF cancer research grants, Hebrew University of Jerusalem.
  9. ^ Dr. Asael Lubotzky, MD, Israel Cancer Research Fund.
  10. ^ The James Sivartsen Prize in Cancer Research, The Hebrew University, 2019.
  11. ^ Congratulations to Dr. Asael Lubotzky and the team of researchers from Hebrew University who were chosen to receive one of the grants for half a million dollars from the Bill & Melinda Gates Foundation, Shaare Zedek Medical Center news, February 26, 2020.
  12. ^ Asael Lubotzy, MD, PhD, Hebrew University, Alzheimer's Drug Discovery Foundation, 2021.
  13. ^ PhD Thesis Defense - Dr. Asael Lubotzky, The Department of Developmental Biology and Cancer Research, The Hebrew University, 2021.
  14. ^ Lubotzky, Asael et al. "Liquid biopsy reveals collateral tissue damage in cancer." JCI insight vol. 7,2 (2022), PMID 35076021
  15. ^ Rothschild Fellows, Yad Hanadiv, 2022.
  16. ^ Siegel-Itzkovich, Judy (19 July 2022). "Think you have schizophrenia? A simple blood test can answer". Jerusalem Post.
  17. ^ Lubotzky, Asael et al. "Elevated brain-derived cell-free DNA among patients with first psychotic episode – a proof-of-concept study." Elife. 2022 Jun 14;11:e76391, PMID 35699419
  18. ^ Ben Barres Spotlight Awards: Announcing the winners for 2023, eLife, 2023.
  19. ^ A wounded soldier who became one of Israel's best-selling authors has become a father, Maayana Miskin, Arutz Sheva, September 16, 2010.
  20. ^ Dr. Asael Lubotzky, Rohr Jewish Learning Institute.
  21. ^ Not My Last Journey, Yedioth Ahronoth, 2017.
  22. ^ Dr. Lubotzky won The Leitersdorf Award for significant contribution to the arts, Shaare Zedek Medical Center, July 2017.
  23. ^ Inspirational speaker, Asael Lubotzky, M.D., who spoke about his victory overcoming medical injuries received in the 2006 Lebanon War, American Healthcare Professionals and Friends for Medicine in Israel, December 16, 2012.
  24. ^ Physician shows medical Birthright group that blending profession and Judaism works, The Jewish News, January 10, 2015.
  25. ^ A Hero's Struggle – Dr. Asael Lubotzky, Rohr Jewish Learning Institute.
  26. ^ Author Corner, The Toby Press, Koren Publishers Jerusalem.
  27. ^ Alush, Korin Elbaz (June 26, 2019). "Father and grandfather swoop into ensure smooth delivery". Ynetnews.

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