Dr. Vijay Nambiar is a skilled and renowned neurosurgeon. He lives with his wife, Dr. Nalini, and their two children. Both doctors work at Apothecary Hospital. The film begins with Nambiar being admitted to the hospital because of a motor vehicle accident. He has suffered a brain injury, and his chance of survival seems slim. Subin Joseph, a patient of Nambiar's, comes to visit him.
Subin recounts his experience at the hospital under Nambiar's care. The hospital is revealed to be run greedily, with patients being subjected to expensive and unnecessary tests and medicines. Nambiar is a doctor with a good reputation, but is forced by the management to run clinical trials for new drugs. He realizes that such trials are necessary for progress, but the lack of ethical protocol and the side effects of such drugs turn the patients' lives into a living hell.
This dilemma consumes him, causing him to have hallucinations of his clinical trial patients. His soul is locked in a surreal struggle between the good and the bad actions of his work. His accident resulted from such an episode wherein he fell to the road in a fit of panic. Finally, he is redeemed with the realization that his work has saved thousands, compared to the few lives destroyed by his actions. Should he live, he would go on to save even more lives.
Nambiar returns to life as a changed man. He confronts the hospital board about their actions. He reminds them of the definition of 'Apothecary' used years back to refer to doctors who treated village folk with their medicines. Stating that the hospital merely retains that name, he leaves the hospital to set up a charitable institution. Nalini and several of the hospital staff and patients accompany him on his new journey.
Paresh C. Palicha of Rediff Movies praised Suresh Gopi's performance and noted that the film could have been better.[5] Nicy, V.P. of International Business Times, wrote that Apothecary is a must watch. She also praised performance of Jayasurya.[6]