Cruz has written numerous books focusing on themes of home, gender, race, displacement, and working class life.
Cruz published her first novel Soledad in 2001 and her second novel, Let It Rain Coffee in 2005, both with Simon & Schuster. Her third novel, Dominicana (2019), which she published with Flatiron Books, received widespread acclaim.[5][6]Publishers Weekly described the work as "Enthralling...Cruz's winning novel will linger in the reader’s mind long after the close of the story."[7]NBC described Dominicana as "one of the most evocative and empowering immigrant stories of our time."[8] In 2022, Cruz published her fourth novel, How Not to Drown in a Glass of Water, also with Flatiron Books.
Cruz has received numerous grants for her teaching and writing, including the Barbara Deming Award, New York Foundation for the Arts Fellowship, Camargo Fellowship, Van Lier Literary Fellowship, and NALAC Fund for the Arts Fellowship.[4] She has also been awarded residencies: Yaddo, The Macdowell Colony, Fundacion Valparaiso, La Napoule Foundation, and The Millay Colony.[4]
In 2021, Cruz was awarded the Gina Berriault Award. The award is given annually to a writer who has shown a love for storytelling and a commitment to helping young writers.[11]