On September 2, 2018, the Rays promoted Velazquez to the major leagues for the first time.[19] He recorded three hits in ten at-bats playing off the bench. Despite only playing 34+2⁄3 innings and making only one start, Velazquez played at least one inning at six positions (second base, shortstop, third base, left field, center field, and right field).[20]
Cleveland Indians
On July 3, 2019, the Rays traded Velazquez to the Cleveland Indians in exchange for international bonus pool allotments.[21] In a corresponding move the Indians designated Chih-Wei Hu for assignment.[22] Cleveland assigned Velazquez to the Columbus Clippers of the International League, and promoted him to the major leagues on September 17.[23] He appeared in five games for Cleveland, registering one hit, a double, in 11 at bats.[24]
Velazquez was designated for assignment on February 14, 2020, when they signed Domingo Santana.[24]
Baltimore Orioles
Velazquez was claimed off waivers by the Baltimore Orioles on February 19, 2020.[25] In 2020 for the Orioles, Velazquez slashed .159/.274/.206 with no home runs and three RBI.[26] On October 29, Velazquez was outrighted off of the 40-man roster.[27] He became a free agent on November 2.[28]
New York Yankees
On December 16, 2020, Velazquez signed a minor league contract with the New York Yankees organization.[29] On July 16, 2021, Velazquez was released by the Yankees organization, but re-signed with the team the next day on a new minor league deal.[30] On August 9, the Yankees promoted Velazquez to the major leagues.[31] Playing for the Yankees was a dream come true for Velazquez. He had grown up idolizing Derek Jeter.[32] On August 10, Velazquez scored his first Yankees run on a wild pitch.[citation needed]
In seven at bats in a series against the Boston Red Sox, Velazquez tallied three run-scoring hits with 4 RBI, (one run of his own, and a stolen base). After closing out the final game with a diving catch at shortstop and a difficult throw to first base from deep in the hole, his teammates awarded him the well-deserved "game belt" in recognition of his contributions to the series sweep that saw the team move into first place of the Wild Card standings; two games ahead of the rival Red Sox.[33]
On September 11, following the team’s victory over the New York Mets, Velazquez was demoted to the Yankees’s Triple-A affiliate, the Scranton/Wilkes-Barre RailRiders. He was recalled to the Yankees prior to the penultimate game of the regular season on October 2.[36]
Los Angeles Angels
On November 5, 2021, Velazquez was claimed off waivers by the Los Angeles Angels.[37] He opened the 2022 season with the Salt Lake Bees of the Triple-A Pacific Coast League and was promoted to the major leagues on April 12 to be the starting shortstop after David Fletcher was injured.[2] On September 13, 2022, during a game against the Cleveland Guardians, Velazquez suffered a right meniscus tear, ending his season. In 125 games, Velazquez batted .196/.236/.304 with 10 home runs and 37 RBIs.[38]
On March 1, 2023, Velazquez gave up switch hitting and focused primarily on being a right-handed hitter. He has since gone back to being a switch hitter.[39] Velazquez was optioned to Triple-A Salt Lake to begin the 2023 season.[40] In 54 games for the Angels, he hit .173/.264/.284 with 2 home runs, 3 RBI, and 13 stolen bases.
Atlanta Braves
On September 5, 2023, Velazquez was claimed off waivers by the Atlanta Braves.[41] In 14 games for the Triple–A Gwinnett Stripers, he hit .217/.266/.250 with no home runs and four RBI. Following the season on November 1, Velazquez was removed from the 40–man roster and sent outright to Triple–A Gwinnett.[42] However, Velazquez rejected the assignment and elected free agency.[43]
On November 24, 2023, Velazquez re-signed with the Braves on a minor league contract.[44] He played in 118 games for Gwinnett in 2024, slashing .242/.298/.394 with 16 home runs, 48 RBI, and 33 stolen bases. Velazquez elected free agency following the season on November 4, 2024.[45]
New York Yankees (second stint)
On January 3, 2025, Velazquez signed a minor league contract with the New York Yankees.[46]