In 1900, at the founding of the Kaunas Society of Agriculture, Meysztowicz was elected its vice-chairperson, and in 1904, he was unanimously voted to receive the title of the honorary member. Under his leadership, the society handled issues of resettling villages and establishing retirement funds for agricultural workers. From his initiative were also founded the Kaunas Mutual Fire Insurance Society, of which he was also the chairperson, and a number of other agricultural unions that served to unite the activities of rural owners.[1][2]
Because of his participation in the unveiling ceremony of the Monument of Catherine the Great in Vilnius, on 23 September 1904, he was disliked by Polish nationalists.[1][2]
He was also the chairperson of the Vilnius Land Bank from 1918 to 1926, and from 1932 to 1939.[1][2]
After returning to Lithuania in 1917, he became a prominent member of the Borderlands Bisons, a conservative group of Lithuanian Poles, who sought to unite Lithuania with Poland. From 1917 to 1918, he was also a prominent member of the National Conservative Party.[4]
After Lithuania has declared independence from Russia in 1918, he fled to Polish-occupied Vilnius, and his estate was confiscated by the government. From 21 November 1921 to 6 April 1922, he was the chairperson of the Provisional Governing Commission of the Republic of Central Lithuania.[1][2]
From 2 October 1926 to 22 December 1928, he was the Minister of Justice and the Chief Prosecutor of Poland. He supported Polish expansion to the east, and advocated for the polonization of ethnic minorities in eastern Poland.[1]