The Alabama cave shrimp is only known from five caves, all in Madison County, Alabama.[3]Shelta Cave is the species' type locality, but viable populations have only been confirmed in Bobcat Cave and the complex comprising Hering Cave, Glover Cave and Brazelton Cave.
The closest relative of the Alabama cave shrimp is the Kentucky cave shrimp, Palaemonias ganteri, which lives in Mammoth Cave National Park, Kentucky.[3] The two species can be distinguished by size (P. alabamae being larger than P. ganteri), the longer rostrum in P. alabamae, and the greater number of spines on the rostrum of P. alabamae.[3]