In early years as ingénieur des mines, Delesse investigated and described various new minerals; he proceeded afterward to the study of rocks, devising new methods for their determination, and giving particular descriptions of melaphyre, arkose, porphyry, syenite, and others. The igneous rocks of the Vosges, and those of the Alps, Corsica, etc., and the subject of metamorphism occupied his attention. He also prepared in 1858 geological and hydrological maps of Paris, with reference to the underground water, similar maps of the départements of the Seine and Seine-et-Marne, and an agronomic map of the Seine-et-Marne (1880), in which he showed the relation that exists between the physical and chemical characters of the soil and the geological structure.[4]
The annual Revue des progrès de géologie of Delesse, undertaken with the assistance (1860–1865) of Auguste Laugel and afterwards (1865–1878) of Albert de Lapparent, was carried on from 1860 to 1880. His observations on the lithology of the deposits accumulated beneath the sea were of special interest and importance. His separate publications were: Recherches sur l'origine des roches (Paris, 1865); Étude sur le métamorphisme des roches (1869), Lithologie des mers de France et des mers principales du globe (2 vols. and atlas, 1871).[4]