The club was founded in 1927 as A.C. Sangiovannese 1927.
Sangiovannese played in Serie C2 from 2000–01, following their promotion from Serie D, then reaching Serie C1 in 2003–04. The club played in this league until 2007–08 when they were relegated to Lega Pro Seconda Divisione. Sangio would remain in this division for three seasons until 2010–11.