Redirect to:
PMID 12167863. S2CID 4403228. Takaori A (December 2005). "[Antiviral defense by APOBEC3 family proteins]". Uirusu (in Japanese). 55 (2): 267–72. doi:10.2222/jsv...
Click to read more »host boundaries are usually well kept because of the limited types of APOBEC3 enzymes that viral infectivity factor can neutralize. Consensus in the...
Click to read more »cytosine residues in nascent retroviral cDNA. APOBEC3D is one of the human APOBEC3 enzymes involved in restriction of HIV-1. HIV-1 Vif counteracts APOBEC3D...
Click to read more »catalytic polypeptide-like 3A, also known as APOBEC3A, or A3A is a gene of the APOBEC3 family found in primates, including humans, and some other mammals. It...
Click to read more »tumors. A 2013 review discussed the structural and biophysical aspects of APOBEC3 family enzymes. Many of the APOBEC protein features are described in the...
Click to read more »genomes and diagnostics. Wain-Hobson's most recent work involves the role of APOBEC3 in cancer and other human diseases. Wain-Hobson is a co-founder of Invectys...
Click to read more »Accessory proteins: Nef: negative factor Vpr: regulatory protein Vif: APOBEC3 inhibitor Vpu/Vpx: unique to each type of HIV p6: part of gag Serological...
Click to read more »Messer, RJ; Yonemoto, W; Chesebro, B; Hasenkrug, KJ; Greene, WC (2008). "Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus...
Click to read more »(ed.). "Evidence for Restriction of Ancient Primate Gammaretroviruses by APOBEC3 but Not TRIM5α Proteins". PLOS Pathogens. 4 (10) e1000181. doi:10.1371/journal...
Click to read more »Another study examined how replication stress affected APOBEC3B activity. APOBEC3 (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3) has...
Click to read more »Landau NR (2007). "Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains". The Journal of Biological Chemistry. 281 (48):...
Click to read more »on 22 July 2022. Retrieved 22 July 2022. "observations about putative APOBEC3 deaminase editing driving short-term evolution of MPXV since 2017". Virological...
Click to read more »and Caprine arthritis encephalitis virus (Pfam PF07401). The mamallian APOBEC3 enzymes are in an arms race with Vifs found in those viruses, actively...
Click to read more »seen C→T mutation in kataegis.[citation needed] Among the APOBEC family, APOBEC3 subfamily are responsible for protection against retroviruses such as HIV(known...
Click to read more »associated with high burden of indels with microhomology at the breakpoints. APOBEC3 family of cytidine deaminase enzymes respond to viral infections by editing...
Click to read more »of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo". Journal of Virology. 85 (15):...
Click to read more »PMID 11331580. Cullen BR (Feb 2006). "Role and mechanism of action of the APOBEC3 family of antiretroviral resistance factors". Journal of Virology. 80 (3):...
Click to read more »published in Clinical Cancer Research “Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations...
Click to read more »Wain-Hobson S (April 2008). "Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions". Science. 320 (5873): 230–3. Bibcode:2008Sci...
Click to read more »viral replication, as it counteracts the innate antiretroviral activity of APOBEC3 family defense factors by obstructing their incorporation into virions...
Click to read more »Ludmil B. (February 2022). "Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA". Nature. 602 (7897): 510–517. Bibcode:2022Natur.602...
Click to read more »Lovsin, Nika; Peterlin, B. Matija; Ross, Susan R. (28 January 2007). "APOBEC3 inhibits mouse mammary tumour virus replication in vivo". Nature. 445 (7130):...
Click to read more »Errando M, Bieniasz PD (August 2016). "The RNA Binding Specificity of Human APOBEC3 Proteins Resembles That of HIV-1 Nucleocapsid". PLOS Pathogens. 12 (8)...
Click to read more »Peng G, Lei KJ, Jin W, Greenwell-Wild T, Wahl SM (2006). "Induction of APOBEC3 family proteins, a defensive maneuver underlying interferon-induced anti-HIV-1...
Click to read more »