The unit took part in Operation Enduring Freedom with the mission to provide force protection and mission command for the five base clusters in Kabul. Between 18 May 2013 and 31 January 2014, the 226th MEB participated in combat and non-combat missions in support of the International Security Assistance Force. For the service in Afghanistan, the brigade was awarded the Meritorious Unit Commendation on 16 May 2014.[6]