American college football season
The 2021 Colorado Buffaloes football team represented the University of Colorado Boulder during the 2021 NCAA Division I FBS football season. The Buffaloes were led by second-year head coach Karl Dorrell. They played their home games on campus at Folsom Field as a member of the South Division of the Pac-12 Conference.
Schedule
Date | Time | Opponent | Site | TV | Result | Attendance |
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| 7:00 p.m. | Northern Colorado* | | P12N | W 35–7 | 44,153 |
September 11 | 1:30 p.m. | vs. No. 5 Texas A&M* | | FOX | L 7–10 | 61,203 |
September 18 | 11:00 a.m. | Minnesota* | | P12N | L 0–30 | 47,482 |
September 25 | 8:30 p.m. | at Arizona State | | ESPNU | L 13–35 | 44,803 |
October 2 | 12:00 p.m. | USC | | P12N | L 14–37 | 48,197 |
October 16 | 1:30 p.m. | Arizona | | P12N | W 34–0 | 49,806 |
October 23 | 1:30 p.m. | at California | | P12N | L 3–26 | 36,264 |
October 30 | 1:30 p.m. | at No. 7 Oregon | | FOX | L 29–52 | 51,449 |
November 6 | 5:00 p.m. | Oregon State | | P12N | W 37–34 2OT | 47,984 |
November 13 | 7:00 p.m. | at UCLA | | P12N | L 20–44 | 36,573 |
November 20 | 1:00 p.m. | Washington | | P12N | W 20–17 | 41,284 |
| 2:00 p.m. | at No. 19 Utah | | FOX | L 13–28 | 51,538 |
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Coaching staff
- William Vlachos took over as the offensive line coach when Rodrigue was fired
References
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National championship seasons in bold |