The 2020–21 Uganda Premier League was the 53rd season of the Uganda Premier League, the top-tier football league in Uganda. The season ended prematurely due to a 42-day lockdown as a result of the COVID-19 pandemic with only four rounds to play.[1] FUFA announced Express FC the winners in July 2021 under league regulations that allow a winner to be declared if the league is more than 75% complete.[2] Because the cup was cancelled during the semi-final stage, runners-up URA were selected to represent Uganda in the Confederation Cup.[3]
MYDA and Kitara were already statistically relegated by the time the league was suspended, while Kyetume FC were relegated when the league ended early.[1]