Julie Corletto and Madison Browne both made their 50th ANZ Championship appearances in Round 5 against Queensland Firebirds.
Chelsey Tregear made her 50th ANZ Championship appearance in Round 14 against Southern Steel. Tregear subsequently announced her retirement at the Vixens awards ceremony.
On 2, 3 and 4 March, Waikato Bay of Plenty Magic hosted a pre-season tournament at the TECT Arena in Tauranga. For the first time since 2008, all ten ANZ Championship teams competed at the same tournament. The ten teams were divided into two pools of five. Teams within each pool played each other once and the winners qualified for the final. Melbourne Vixens won their pool but subsequently lost the final 50–30 to Queensland Firebirds.
Melbourne Vixens finished the regular season as minor premiers. After winning their first six matches, they lost to New South Wales Swifts in Round 7. They then lost three successive matches, another to Swifts and one to Northern Mystics. On 20 May in Round 8, against Mystics, Vixens were undone by Mystics defender Anna Harrison and her Harrison Hoist. Harrison made several vital blocks while being hoisted rugby union lineout-style by her defensive partners, helping Mystics secure a 49–45 win. However, Vixens successively claimed the minor premiership with three wins in the final three rounds. [1][2][16][17]