2-Ethoxyethanol

2-Ethoxyethanol
2-Ethoxyethanol
Names
Preferred IUPAC name
2-Ethoxyethanol
Other names
Cellosolve
ethylene glycol ethyl ether
oxitol
Ethyl Cellosolve
EGEE
Identifiers
3D model (JSmol)
1098271
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.003.459 Edit this at Wikidata
EC Number
  • 203-804-1
82142
KEGG
RTECS number
  • KK8050000
UNII
UN number 1171
  • InChI=1S/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
    Key: ZNQVEEAIQZEUHB-UHFFFAOYSA-N
  • InChI=1/C4H10O2/c1-2-6-4-3-5/h5H,2-4H2,1H3
    Key: ZNQVEEAIQZEUHB-UHFFFAOYAD
  • CCOCCO
Properties
C4H10O2
Molar mass 90.122 g·mol−1
Appearance clear liquid
Odor sweet, ether-like
Density 0.930 g/cm3, liquid
Melting point −70 °C (−94 °F; 203 K)
Boiling point 135 °C (275 °F; 408 K)
miscible
Vapor pressure 4 mmHg (20°C)[1]
Hazards
GHS labelling:
GHS02: FlammableGHS06: ToxicGHS07: Exclamation markGHS08: Health hazard
Danger
H226, H302, H331, H360
P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P281, P301+P312, P303+P361+P353, P304+P340, P308+P313, P311, P321, P330, P370+P378, P403+P233, P403+P235, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 2: Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury. E.g. chloroformFlammability 2: Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur. Flash point between 38 and 93 °C (100 and 200 °F). E.g. diesel fuelInstability (yellow): no hazard codeSpecial hazards (white): no code
2
2
Flash point 44 °C (111 °F; 317 K)
Explosive limits 1.7%-15.6%[1]
Lethal dose or concentration (LD, LC):
2451 mg/kg (mouse, oral)
2125 mg/kg (rat, oral)[2]
2000 ppm (rat, 7 hr)
1820 ppm (mouse, 7 hr)[2]
3000 ppm (guinea pig, 24 hr)[2]
NIOSH (US health exposure limits):
PEL (Permissible)
 TWA 200 ppm (740 mg/m3) [skin][1]
REL (Recommended)
 TWA 0.5 ppm (1.8 mg/m3) [skin][1]
IDLH (Immediate danger)
 500 ppm[1]
Related compounds
Related ethers
 2-Propoxyethanol
2-Butoxyethanol
Related compounds
 Ethylene glycol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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2-Ethoxyethanol, also known by the trademark Ethyl cellosolve, is a solvent used widely in commercial and industrial applications. It is a clear, colorless, nearly odorless liquid that is miscible with water, ethanol, diethyl ether, acetone, and ethyl acetate.[3]

2-Ethoxyethanol is manufactured by the reaction of ethylene oxide with ethanol.

As with other glycol ethers, 2-ethoxyethanol has the useful property of being able to dissolve chemically diverse compounds. It will dissolve oils, resins, grease, waxes, nitrocellulose, and lacquers.[3] This is an ideal property as a multi-purpose cleaner, and, therefore, 2-ethoxyethanol is used in products such as varnish removers and degreasing solutions.

References

  1. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0258". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ a b c "2-Ethoxyethanol". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  3. ^ a b National Research Council (U.S.). Subcommittee on Spacecraft Maximum Allowable Concentrations (1996). Spacecraft maximum allowable concentrations for selected airborne contaminants. National Academies Press. p. 189. ISBN 978-0-309-05478-2. Retrieved 19 February 2012.