Risperidon

Risperidon (originalt handelsnavn Risperdal®) er et nyere antipsykotikum der anvendes til behandling af psykotiske tilstande, fx ved skizofreni og mani.[1&

Risperidon
Risperidon
Kliniske data
HandelsnavneRisperanne, Risperdal®, Rispolept Consta
Administrationsvejp.o., i.m.
ATC-kode
Fysiologiske data
MetabolismeLever (CYP2D6)
Juridisk status
Juridisk status
  • DK: B
Farmakokinetiske data
Biotilgængelighed70%
MetabolismeLever (CYP2D6)
Halveringstid20 timer
UdskillelseUrin
Identifikatorer
  • 4-[2-[4-(6-fluorbenzo[d]isoxazol-3-yl)-1-piperidyl]ethyl]-3-methyl-2,6-diazabicyclo[4.4.0]deca-1,3-dien-5-on
CAS-nummer
PubChem CID
DrugBank
CompTox Dashboard (EPA)
ECHA InfoCard100.114.705 Redigér dette på Wikidata
Kemiske og fysiske data
FormelC23H27FN4O2
Molarmasse410,49 g·mol−1
3D-model (JSmol)
  • Cc1c(c(=O)n2c(n1)CCCC2)CCN3CCC(CC3)c4c5ccc(cc5on4)F
  • InChI=InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3
  • Key:RAPZEAPATHNIPO-UHFFFAOYSA-N

Risperidon (originalt handelsnavn Risperdal®) er et nyere antipsykotikum der anvendes til behandling af psykotiske tilstande, fx ved skizofreni og mani.[1] Risperidon anvendes også i lave doser som tillægsbehandling til f.eks. Sertralin i behandlingsrefraktær OCD.[2] Risperidon blev udviklet af Janssen-Cilag og blev først markedsført i 1994. I dag findes mange generiske præparater med stoffet.

Referencer

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