ZHX2

ZHX2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DMP, 3NAU
Dynodwyr
Cyfenwau	ZHX2, AFR1, RAF, zinc fingers and homeoboxes 2
Dynodwyr allanol	OMIM: 609185 HomoloGene: 8968 GeneCards: ZHX2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • protein homodimerization activity • GO:0001106 transcription corepressor activity • metal ion binding • identical protein binding • protein heterodimerization activity • nucleic acid binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell • nucleoplasm • cytosol • cellbilen Prosesau biolegol • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • GO:0045996 negative regulation of transcription, DNA-templated • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • mRNA catabolic process • negative regulation of neuron differentiation • somatic stem cell population maintenance • transcription, DNA-templated • retinal bipolar neuron differentiation • nervous system development • cell differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	22882	n/a
Ensembl	ENSG00000178764	n/a
UniProt	Q9Y6X8	n/a
RefSeq (mRNA)	NM_014943 NM_001362797	n/a
RefSeq (protein)	NP_055758 NP_001349726	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ZHX2 yw ZHX2 a elwir hefyd yn Zinc fingers and homeoboxes protein 2 a Zinc fingers and homeoboxes 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 8, band 8q24.13.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ZHX2.

• RAF
• AFR1

• "Expression of zinc-fingers and homeoboxes 2 in hepatocellular carcinogenesis: a tissue microarray and clinicopathological analysis. ". Neoplasma. 2007. PMID 17447851.
• "Genetic association and gene-smoking interaction study of carotid intima-media thickness at five GWAS-indicated genes: the Bogalusa Heart Study. ". Gene. 2015. PMID 25746325.
• "Proliferation and osteo/odontogenic differentiation of stem cells from apical papilla regulated by Zinc fingers and homeoboxes 2: An in vitro study. ". Biochem Biophys Res Commun. 2016. PMID 26679602.
• "Transcriptional deregulation of homeobox gene ZHX2 in Hodgkin lymphoma. ". Leuk Res. 2012. PMID 22078940.
• "Lack of association of G779A ZHX-2 gene variant with HbF levels in β-thalassemia major.". Eur J Haematol. 2011. PMID 21443521.