UNC45A

2DBA

UNC45A
UNC45A
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauUNC45A, GC-UNC45, GCUNC-45, GCUNC45, IRO039700, SMAP-1, SMAP1, UNC-45A, unc-45 myosin chaperone A, OOHE
Dynodwyr allanolOMIM: 611219 HomoloGene: 32423 GeneCards: UNC45A
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

55898

n/a

Ensembl

ENSG00000140553

n/a

UniProt

Q9H3U1

n/a

RefSeq (mRNA)

n/a

RefSeq (protein)

NP_001034764
NP_001310548
NP_001310549
NP_001310550
NP_061141

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UNC45A yw UNC45A a elwir hefyd yn Unc-45 myosin chaperone A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q26.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UNC45A.

  • SMAP1
  • SMAP-1
  • GCUNC45
  • UNC-45A
  • GC-UNC45
  • GCUNC-45
  • IRO039700

Llyfryddiaeth

  • "Differential turnover of myosin chaperone UNC-45A isoforms increases in metastatic human breast cancer. ". J Mol Biol. 2011. PMID 21802425.
  • "Myosin II co-chaperone general cell UNC-45 overexpression is associated with ovarian cancer, rapid proliferation, and motility. ". Am J Pathol. 2007. PMID 17872978.
  • "UNC-45a promotes myosin folding and stress fiber assembly. ". J Cell Biol. 2017. PMID 29055011.
  • "UNC-45A is required for neurite extension via controlling NMII activation. ". Mol Biol Cell. 2017. PMID 28356421.
  • "UNC-45A Is a Nonmuscle Myosin IIA Chaperone Required for NK Cell Cytotoxicity via Control of Lytic Granule Secretion.". J Immunol. 2015. PMID 26438524.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ UNC45A - Cronfa NCBI

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