UBE4A

1WGM

UBE4A
UBE4A
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauUBE4A, E4, UBOX2, UFD2, ubiquitination factor E4A, NEDHMS
Dynodwyr allanolOMIM: 603753 HomoloGene: 3517 GeneCards: UBE4A
EC number2.3.2.27
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

9354

n/a

Ensembl

ENSG00000110344

n/a

UniProt

Q14139

n/a

RefSeq (mRNA)

NM_004788
NM_001204077

n/a

RefSeq (protein)

NP_001191006
NP_004779

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn UBE4A yw UBE4A a elwir hefyd yn Ubiquitination factor E4A (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q23.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn UBE4A.

  • E4
  • UFD2
  • UBOX2

Llyfryddiaeth

  • "SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2. ". Nat Commun. 2014. PMID 24457997.
  • "[Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues]. ". Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007. PMID 17553343.
  • "Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease. ". Inflamm Bowel Dis. 2008. PMID 18069675.
  • "Expression analysis of the gene encoding for the U-box-type ubiquitin ligase UBE4A in human tissues. ". Gene. 2004. PMID 15019985.
  • "The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI).". IUBMB Life. 2017. PMID 27862841.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ UBE4A - Cronfa NCBI

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