TREM1

TREM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1Q8M, 1SMO
Dynodwyr
Cyfenwau	TREM1, CD354, TREM-1, triggering receptor expressed on myeloid cells 1
Dynodwyr allanol	OMIM: 605085 HomoloGene: 10243 GeneCards: TREM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • scaffold protein binding • signaling receptor activity Cydrannau o'r gell • integral component of membrane • bilen • cellbilen • extracellular region • intracellular anatomical structure Prosesau biolegol • GO:0007243 intracellular signal transduction • humoral immune response • regulation of immune response • innate immune response • leukocyte migration • acute inflammatory response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54210	n/a
Ensembl	ENSG00000124731	n/a
UniProt	Q9NP99	n/a
RefSeq (mRNA)	NM_001242589 NM_001242590 NM_018643	n/a
RefSeq (protein)	NP_001229518 NP_001229519 NP_061113	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TREM1 yw TREM1 a elwir hefyd yn Triggering receptor expressed on myeloid cells 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TREM1.

• CD354
• TREM-1

• "Knockdown of TREM-1 suppresses IL-1β-induced chondrocyte injury via inhibiting the NF-κB pathway. ". Biochem Biophys Res Commun. 2017. PMID 27932245.
• "Significance of soluble triggering receptor expressed on myeloid cells-1 elevation in patients admitted to the intensive care unit with sepsis. ". BMC Infect Dis. 2016. PMID 27729010.
• "TREM-1 SNP rs2234246 regulates TREM-1 protein and mRNA levels and is associated with plasma levels of L-selectin. ". PLoS One. 2017. PMID 28771614.
• "Urine TREM-1 as a marker of urinary tract infection in children. ". J Int Med Res. 2017. PMID 28367708.
• "Increased expression of triggering receptor expressed on myeloid cells-1 in the population with obesity and insulin resistance.". Obesity (Silver Spring). 2017. PMID 28111922.