THOP1

1S4B, 2O36

THOP1
THOP1
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauTHOP1, EP24.15, MEPD_HUMAN, MP78, TOP, thimet oligopeptidase 1
Dynodwyr allanolOMIM: 601117 HomoloGene: 55726 GeneCards: THOP1
EC number3.4.24.15
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

7064

n/a

Ensembl

ENSG00000172009

n/a

UniProt

P52888

n/a

RefSeq (mRNA)

NM_003249

n/a

RefSeq (protein)

NP_003240

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn THOP1 yw THOP1 a elwir hefyd yn Thimet oligopeptidase a Thimet oligopeptidase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19p13.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn THOP1.

  • TOP
  • MP78
  • EP24.15
  • MEPD_HUMAN

Llyfryddiaeth

  • "Inhibition of thimet oligopeptidase by siRNA alters specific intracellular peptides and potentiates isoproterenol signal transduction. ". FEBS Lett. 2012. PMID 22796113.
  • "Analysis of intracellular substrates and products of thimet oligopeptidase in human embryonic kidney 293 cells. ". J Biol Chem. 2009. PMID 19282285.
  • "Expression of THOP1 and its relationship to prognosis in non-small cell lung cancer. ". PLoS One. 2014. PMID 25180910.
  • "Expression analysis of THOP1 in background liver, a prognostic predictive factor in hepatocellular carcinoma, extracted by multiarray analysis. ". Ann Surg Oncol. 2014. PMID 24604581.
  • "Recycling of the high valence States of heme proteins by cysteine residues of THIMET-oligopeptidase.". PLoS One. 2013. PMID 24223886.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ THOP1 - Cronfa NCBI

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