THBS2

THBS2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YO8, 2RHP
Dynodwyr
Cyfenwau	THBS2, TSP2, thrombospondin 2
Dynodwyr allanol	OMIM: 188061 HomoloGene: 2438 GeneCards: THBS2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • GO:0001948, GO:0016582 protein binding • heparin binding • extracellular matrix structural constituent Cydrannau o'r gell • GO:0005578 extracellular matrix • platelet alpha granule • basement membrane • extracellular region • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • positive regulation of synapse assembly • negative regulation of angiogenesis • cell adhesion • extracellular matrix organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	7058	n/a
Ensembl	ENSG00000186340	n/a
UniProt	P35442	n/a
RefSeq (mRNA)	NM_003247	n/a
RefSeq (protein)	NP_003238 NP_001368868 NP_001368869 NP_001368870 NP_001368871	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn THBS2 yw THBS2 a elwir hefyd yn Thrombospondin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q27.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn THBS2.

• TSP2

• "Circulating thrombospondin-2 reflects disease severity and predicts outcome of heart failure with reduced ejection fraction. ". Circ J. 2014. PMID 24500070.
• "Thrombospondin-2 secreted by human umbilical cord blood-derived mesenchymal stem cells promotes chondrogenic differentiation. ". Stem Cells. 2013. PMID 23843355.
• "Autocrine Action of Thrombospondin-2 Determines the Chondrogenic Differentiation Potential and Suppresses Hypertrophic Maturation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells. ". Stem Cells. 2015. PMID 26235673.
• "Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer. ". Mol Cancer. 2014. PMID 25262009.
• "Secretome profiling of primary cells reveals that THBS2 is a salivary biomarker of oral cavity squamous cell carcinoma.". J Proteome Res. 2014. PMID 24708169.