TBP

TBP
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	1TGH, 1C9B, 1JFI, 1NVP, 4ROC, 4ROE, 4ROD, 5IY9, 5IYA, 5FUR, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Dynodwyr
Cyfenwau	TBP, GTF2D, GTF2D1, HDL4, SCA17, TFIID, TATA-box binding protein, TATA-binding protein, TBP1
Dynodwyr allanol	OMIM: 600075 HomoloGene: 2404 GeneCards: TBP
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• DNA binding; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • transcription factor binding; • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding; • GO:0001948, GO:0016582 protein binding; • enzyme binding; • TFIIB-class transcription factor binding; • aryl hydrocarbon receptor binding; • GO:0001158 cis-regulatory region sequence-specific DNA binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • RNA polymerase III general transcription initiation factor activity; • GO:0000983 RNA polymerase II general transcription initiation factor activity; • RNA polymerase II core promoter sequence-specific DNA binding; • RNA polymerase III transcription regulatory region sequence-specific DNA binding;
Cydrannau o'r gell	• cytoplasm; • transcription factor TFIID complex; • male pronucleus; • female pronucleus; • nucleoplasm; • transcription factor TFIIA complex; • pronucleus; • cnewyllyn cell; • transcription preinitiation complex; • GO:0009327 protein-containing complex; • transcription factor TFIIIB complex; • transcription regulator complex;
Prosesau biolegol	• termination of RNA polymerase I transcription; • epigenetic maintenance of chromatin in transcription-competent conformation; • GO:0009373 regulation of transcription, DNA-templated; • transcription initiation from RNA polymerase I promoter; • transcription, DNA-templated; • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated; • spermatogenesis; • DNA-templated transcription, initiation; • transcription initiation from RNA polymerase II promoter; • snRNA transcription by RNA polymerase II; • regulation of signal transduction by p53 class mediator; • GO:0022415 viral process; • regulation of transcription by RNA polymerase III; • transcription by RNA polymerase II; • transcription by RNA polymerase III; • RNA polymerase II preinitiation complex assembly; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II; • RNA polymerase III preinitiation complex assembly; • GO:0001183 transcription elongation from RNA polymerase I promoter;
	Sources:Amigo / QuickGO
Orthologau
	6908
	n/a
	ENSG00000112592
	n/a
	P20226
	n/a
	NM_003194; NM_001172085
	n/a
	NP_001165556; NP_003185
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TBP yw TBP a elwir hefyd yn TATA-box binding protein (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q27.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TBP.

HDL4
GTF2D
SCA17
TFIID
GTF2D1

Llyfryddiaeth

"Doubly Spliced RNA of Hepatitis B Virus Suppresses Viral Transcription via TATA-Binding Protein and Induces Stress Granule Assembly. ". J Virol. 2015. PMID 26339052.
"Multivalent engagement of TFIID to nucleosomes. ". PLoS One. 2013. PMID 24039962.
"Human TFIID binds to core promoter DNA in a reorganized structural state. ". Cell. 2013. PMID 23332750.
"TATA binding proteins can recognize nontraditional DNA sequences. ". Biophys J. 2012. PMID 23062343.
"Severe and rapidly progressing cognitive phenotype in a SCA17-family with only marginally expanded CAG/CAA repeats in the TATA-box binding protein gene: a case report.". BMC Neurol. 2012. PMID 22889412.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] TBP - Cronfa NCBI

[1]

[2]

TBP

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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