TASP1

2A8I, 2A8J, 2A8L, 2A8M

TASP1
TASP1
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauTASP1, C20orf13, dJ585I14.2, taspase 1, SULEHS
Dynodwyr allanolOMIM: 608270 HomoloGene: 9795 GeneCards: TASP1
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

55617

n/a

Ensembl

ENSG00000089123

n/a

UniProt

Q9H6P5

n/a

RefSeq (mRNA)

NM_017714
NM_001323602
NM_001323603
NM_001323604

n/a

RefSeq (protein)

NP_001310531
NP_001310532
NP_001310533
NP_060184

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TASP1 yw TASP1 a elwir hefyd yn Taspase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 20, band 20p12.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TASP1.

  • C20orf13
  • dJ585I14.2

Llyfryddiaeth

  • "Overexpression of the catalytically impaired Taspase1 T234V or Taspase1 D233A variants does not have a dominant negative effect in T(4;11) leukemia cells. ". PLoS One. 2012. PMID 22570686.
  • "Cell-based analysis of structure-function activity of threonine aspartase 1. ". J Biol Chem. 2011. PMID 21084304.
  • "Taspase 1: A protease with many biological surprises. ". Mol Cell Oncol. 2015. PMID 27308523.
  • "Taspase1: a 'misunderstood' protease with translational cancer relevance. ". Oncogene. 2016. PMID 26657154.
  • "Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4-MLL Fusion Protein.". EBioMedicine. 2015. PMID 26137584.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ TASP1 - Cronfa NCBI

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