TAGLN

1UJO

TAGLN
TAGLN
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauTAGLN, SM22, SMCC, TAGLN1, WS3-10, transgelin, SM22-alpha
Dynodwyr allanolOMIM: 600818 HomoloGene: 2398 GeneCards: TAGLN
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

6876

n/a

Ensembl

ENSG00000149591

n/a

UniProt

Q01995

n/a

RefSeq (mRNA)

NM_003186
NM_001001522

n/a

RefSeq (protein)

NP_001001522
NP_003177

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn TAGLN yw TAGLN a elwir hefyd yn Transgelin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q23.3.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn TAGLN.

  • SM22
  • SMCC
  • TAGLN1
  • WS3-10
  • SM22-alpha

Llyfryddiaeth

  • "The regulatory role of smooth muscle 22 on the proliferation of aortic smooth muscle cells participates in the development of aortic dissection. ". J Vasc Surg. 2017. PMID 27320219.
  • "Transgelin increases metastatic potential of colorectal cancer cells in vivo and alters expression of genes involved in cell motility. ". BMC Cancer. 2016. PMID 26847345.
  • "Transgelin mediates transforming growth factor-β1-induced proliferation of human periodontal ligament cells. ". J Periodontal Res. 2017. PMID 28590058.
  • "SM22 a Plasma Biomarker for Human Transmural Intestinal Ischemia. ". Ann Surg. 2017. PMID 28525410.
  • "Downregulation of transgelin blocks interleukin-8 utilization and suppresses vasculogenic mimicry in breast cancer cells.". Exp Biol Med (Maywood). 2017. PMID 28058861.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ TAGLN - Cronfa NCBI

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