STK10

STK10
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2J7T, 4AOT, 4BC6, 4EQU, 4USD, 4USE, 5AJQ
Dynodwyr
Cyfenwau	STK10, LOK, PRO2729, serine/threonine kinase 10
Dynodwyr allanol	OMIM: 603919 HomoloGene: 38122 GeneCards: STK10
EC number	2.7.11.1
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• transferase activity; • nucleotide binding; • protein kinase activity; • protein homodimerization activity; • kinase activity; • GO:0001948, GO:0016582 protein binding; • identical protein binding; • ATP binding; • protein serine/threonine kinase activity;
Cydrannau o'r gell	• cytoplasm; • bilen; • extracellular exosome; • cellbilen; • specific granule membrane;
Prosesau biolegol	• lymphocyte aggregation; • phosphorylation; • regulation of lymphocyte migration; • protein autophosphorylation; • cell cycle; • protein phosphorylation; • neutrophil degranulation; • regulation of mitotic cell cycle; • GO:0072468 signal transduction; • stress-activated protein kinase signaling cascade; • activation of protein kinase activity; • regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologau
	6793
	n/a
	ENSG00000072786
	n/a
	O94804
	n/a
	NM_005990
	n/a
	NP_005981
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn STK10 yw STK10 a elwir hefyd yn Serine/threonine kinase 10 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q35.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn STK10.

LOK
PRO2729

Llyfryddiaeth

"Sequence analysis of the protein kinase gene family in human testicular germ-cell tumors of adolescents and adults. ". Genes Chromosomes Cancer. 2006. PMID 16175573.
"Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cells. ". Biochem J. 2002. PMID 11903060.
"STK10 missense mutations associated with anti-apoptotic function. ". Oncol Rep. 2013. PMID 23842845.
"Variations in the STK10 gene and possible associations with aspirin-intolerant asthma in a Korean population. ". J Investig Allergol Clin Immunol. 2011. PMID 21905501.
"Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism.". Elife. 2017. PMID 28430576.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] STK10 - Cronfa NCBI

[1]

[2]

STK10

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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