SOX5

SOX5
Dynodwyr
Cyfenwau	SOX5, L-L-SOX5B, L-SOX5F, LAMSHF, SRY-box 5, SRY-box transcription factor 5
Dynodwyr allanol	OMIM: 604975 HomoloGene: 21378 GeneCards: SOX5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • DNA binding • GO:0001948, GO:0016582 protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cnewyllyn cell Prosesau biolegol • cellular response to transforming growth factor beta stimulus • GO:0009373 regulation of transcription, DNA-templated • transcription by RNA polymerase II • positive regulation of cartilage development • positive regulation of chondrocyte differentiation • positive regulation of mesenchymal stem cell differentiation • transcription, DNA-templated • asymmetric neuroblast division • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II • cell fate commitment • GO:0045996 negative regulation of transcription, DNA-templated • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6660	n/a
Ensembl	ENSG00000134532	n/a
UniProt	P35711	n/a
RefSeq (mRNA)	NM_001261414 NM_001261415 NM_006940 NM_152989 NM_178010 NM_001330785	n/a
RefSeq (protein)	NP_001248343 NP_001248344 NP_001317714 NP_008871 NP_694534 NP_821078	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SOX5 yw SOX5 a elwir hefyd yn SRY (Sex determining region Y)-box 5, isoform CRA_f a SRY-box 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12p12.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SOX5.

• "Association study between polymorphisms of PRMT6, PEX10, SOX5, and nonobstructive azoospermia in the Han Chinese population. ". Biol Reprod. 2014. PMID 24648396.
• "Deletion 12p12 involving SOX5 in two children with developmental delay and dysmorphic features. ". Pediatr Neurol. 2013. PMID 23498568.
• "SOX5 promotes epithelial-mesenchymal transition in osteosarcoma via regulation of Snail. ". J BUON. 2017. PMID 28365963.
• "Identification of the SOX5 gene as a novel IGH-involved translocation partner in BCL2-negative follicular lymphoma with t(12;14)(p12.2;q32). ". Int J Hematol. 2015. PMID 26115875.
• "High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.". PLoS One. 2014. PMID 24945754.