SNRPA

SNRPA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1AUD, 1DRZ, 1DZ5, 1FHT, 1M5K, 1M5O, 1M5P, 1M5V, 1NU4, 1OIA, 1SJ3, 1SJ4, 1SJF, 1U6B, 1URN, 1VBX, 1VBY, 1VBZ, 1VC0, 1VC5, 1VC6, 1ZZN, 2A3J, 2NZ4, 2OIH, 2OJ3, 2U1A, 3BO2, 3BO3, 3BO4, 3CUL, 3CUN, 3EGZ, 3G8S, 3G8T, 3G96, 3G9C, 3HHN, 3IIN, 3IRW, 3IWN, 3K0J, 3L3C, 3MUM, 3MUR, 3MUT, 3MUV, 3MXH, 3P49, 3PGW, 3R1H, 3R1L, 3UCU, 3UCZ, 3UD3, 3UD4, 4C4W, 4PR6, 4PRF, 4W90, 4YB1, 5DDO, 5DDR, 5DDQ, 5DDP, 5FJ4
Dynodwyr
Cyfenwau	SNRPA, Mud1, U1-A, U1A, Small nuclear ribonucleoprotein polypeptide A
Dynodwyr allanol	OMIM: 182285 HomoloGene: 3380 GeneCards: SNRPA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • U1 snRNA binding • snRNA stem-loop binding • GO:0001948, GO:0016582 protein binding • RNA binding • nucleic acid binding • U1 snRNP binding • identical protein binding Cydrannau o'r gell • spliceosomal complex • cnewyllyn cell • nucleoplasm • U1 snRNP Prosesau biolegol • mRNA processing • regulation of mRNA polyadenylation • RNA splicing • mRNA splicing, via spliceosome Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	6626	n/a
Ensembl	ENSG00000077312	n/a
UniProt	P09012	n/a
RefSeq (mRNA)	NM_004596	n/a
RefSeq (protein)	NP_004587	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SNRPA yw SNRPA a elwir hefyd yn U1 small nuclear ribonucleoprotein A a Small nuclear ribonucleoprotein polypeptide a (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SNRPA.

• U1A
• Mud1
• U1-A

• "13C NMR relaxation studies of RNA base and ribose nuclei reveal a complex pattern of motions in the RNA binding site for human U1A protein. ". J Mol Biol. 2005. PMID 15890361.
• "Fourteen residues of the U1 snRNP-specific U1A protein are required for homodimerization, cooperative RNA binding, and inhibition of polyadenylation. ". Mol Cell Biol. 2000. PMID 10688667.
• "Multistep kinetics of the U1A-SL2 RNA complex dissociation. ". J Mol Biol. 2011. PMID 21419778.
• "U1A protein-stem loop 2 RNA recognition: prediction of structural differences from protein mutations. ". Biopolymers. 2011. PMID 21384338.
• "A bipartite U1 site represses U1A expression by synergizing with PIE to inhibit nuclear polyadenylation.". RNA. 2007. PMID 17942741.