SKAP2

3OMH

SKAP2
SKAP2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauSKAP2, PRAP, RA70, SAPS, SCAP2, SKAP-HOM, SKAP55R, src kinase associated phosphoprotein 2
Dynodwyr allanolOMIM: 605215 HomoloGene: 2919 GeneCards: SKAP2
Patrwm RNA pattern




Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

8935

n/a

Ensembl

ENSG00000005020

n/a

UniProt

O75563

n/a

RefSeq (mRNA)

NM_003930
NM_001303468

n/a

RefSeq (protein)

NP_001290397
NP_003921

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SKAP2 yw SKAP2 a elwir hefyd yn Src kinase associated phosphoprotein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p15.2.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SKAP2.

  • PRAP
  • RA70
  • SAPS
  • SCAP2
  • SKAP55R
  • SKAP-HOM

Llyfryddiaeth

  • "SKAP2 Promotes Podosome Formation to Facilitate Tumor-Associated Macrophage Infiltration and Metastatic Progression. ". Cancer Res. 2016. PMID 26577701.
  • "The Src substrate SKAP2 regulates actin assembly by interacting with WAVE2 and cortactin proteins. ". J Biol Chem. 2013. PMID 23161539.
  • "Src kinase-associated phosphoprotein2 expression is associated with poor prognosis in non-small cell lung cancer. ". Anticancer Res. 2015. PMID 25862907.
  • "Genome-wide DNA copy number analysis in pancreatic cancer using high-density single nucleotide polymorphism arrays. ". Oncogene. 2008. PMID 17952125.
  • "RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner.". J Biol Chem. 2004. PMID 15166227.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ SKAP2 - Cronfa NCBI

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