SETD7

SETD7
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1H3I, 1MT6, 1MUF, 1N6A, 1N6C, 1O9S, 1XQH, 2F69, 3CBM, 3CBO, 3CBP, 3M53, 3M54, 3M55, 3M56, 3M57, 3M58, 3M59, 3M5A, 3OS5, 3VUZ, 3VV0, 4E47, 4J7F, 4J8O, 4JDS, 4JLG, 5EG2, 5AYF
Dynodwyr
Cyfenwau	SETD7, KMT7, SET7, SET7/9, SET9, SET domain containing lysine methyltransferase 7, SET domain containing 7, histone lysine methyltransferase
Dynodwyr allanol	OMIM: 606594 HomoloGene: 12741 GeneCards: SETD7
EC number	2.1.1.364
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0102674, GO:0102675 methyltransferase activity • transferase activity • p53 binding • chromatin binding • protein-lysine N-methyltransferase activity • GO:0001948, GO:0016582 protein binding • histone-lysine N-methyltransferase activity Cydrannau o'r gell • nucleoplasm • Cromosom • nucleolus • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • peptidyl-lysine monomethylation • transcription, DNA-templated • cellular response to DNA damage stimulus • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • peptidyl-lysine methylation • methylation • heterochromatin organization • peptidyl-lysine dimethylation • histone lysine methylation • response to ethanol • regulation of histone H3-K9 methylation • GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	80854	n/a
Ensembl	ENSG00000145391	n/a
UniProt	Q8WTS6	n/a
RefSeq (mRNA)	NM_001306199 NM_001306200 NM_030648	n/a
RefSeq (protein)	NP_001293128 NP_001293129 NP_085151	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SETD7 yw SETD7 a elwir hefyd yn SET domain containing lysine methyltransferase 7 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q31.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SETD7.

• "A Common Variant in the SETD7 Gene Predicts Serum Lycopene Concentrations. ". Nutrients. 2016. PMID 26861389.
• "Sulfur-Oxygen Chalcogen Bonding Mediates AdoMet Recognition in the Lysine Methyltransferase SET7/9. ". ACS Chem Biol. 2016. PMID 26713889.
• "Increased Expression of SETD7 Promotes Cell Proliferation by Regulating Cell Cycle and Indicates Poor Prognosis in Hepatocellular Carcinoma. ". PLoS One. 2016. PMID 27183310.
• "Tumor suppressor SET9 guides the epigenetic plasticity of breast cancer cells and serves as an early-stage biomarker for predicting metastasis. ". Oncogene. 2016. PMID 27132511.
• "SETD7 Regulates the Differentiation of Human Embryonic Stem Cells.". PLoS One. 2016. PMID 26890252.