SERPINF1

SERPINF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1IMV
Dynodwyr
Cyfenwau	SERPINF1, EPC-1, OI12, OI6, PEDF, PIG35, serpin family F member 1
Dynodwyr allanol	OMIM: 172860 HomoloGene: 1965 GeneCards: SERPINF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • serine-type endopeptidase inhibitor activity Cydrannau o'r gell • GO:0005578 extracellular matrix • melanosome • extracellular region • basement membrane • axon • soma • perinuclear region of cytoplasm • axon hillock • extracellular exosome • extracellular space • collagen-containing extracellular matrix Prosesau biolegol • cellular response to retinoic acid • kidney development • GO:0010260 heneiddio • response to arsenic-containing substance • negative regulation of gene expression • cellular response to dexamethasone stimulus • negative regulation of endothelial cell migration • multicellular organism development • cellular response to cobalt ion • retina development in camera-type eye • short-term memory • negative regulation of epithelial cell proliferation involved in prostate gland development • positive regulation of neuron projection development • ovulation cycle • negative regulation of angiogenesis • cell population proliferation • negative regulation of inflammatory response • cellular response to glucose stimulus • response to acidic pH • negative regulation of neuron death • negative regulation of endopeptidase activity • positive regulation of neurogenesis Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5176	n/a
Ensembl	ENSG00000132386 ENSG00000282307	n/a
UniProt	P36955	n/a
RefSeq (mRNA)	NM_002615 NM_001329903 NM_001329904 NM_001329905	n/a
RefSeq (protein)	NP_001316832 NP_001316833 NP_001316834 NP_002606	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SERPINF1 yw SERPINF1 a elwir hefyd yn Pigment epithelium-derived factor a Serpin family F member 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p13.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SERPINF1.

• "Circulating level of pigment epithelium-derived factor is associated with vascular function and structure: A cross-sectional study. ". Int J Cardiol. 2016. PMID 27716557.
• "Downregulation of pigment epithelium-derived factor is associated with increased epithelial-mesenchymal transition in bladder cancer. ". Panminerva Med. 2017. PMID 27644257.
• "Activation of Complement by Pigment Epithelium-Derived Factor in Rheumatoid Arthritis. ". J Immunol. 2017. PMID 28637898.
• "PEDF Is Associated with the Termination of Chondrocyte Phenotype and Catabolism of Cartilage Tissue. ". Biomed Res Int. 2017. PMID 28191465.
• "Pigment epithelium-derived factor alleviates endothelial injury by inhibiting Wnt/β-catenin pathway.". Lipids Health Dis. 2017. PMID 28173817.