SERPINB5

SERPINB5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WZ9, 1XQG, 1XQJ, 1XU8
Dynodwyr
Cyfenwau	SERPINB5, PI5, maspin, serpin family B member 5
Dynodwyr allanol	OMIM: 154790 HomoloGene: 20580 GeneCards: SERPINB5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • serine-type endopeptidase inhibitor activity Cydrannau o'r gell • cytoplasm • extracellular region • extracellular space Prosesau biolegol • morphogenesis of an epithelium • extracellular matrix organization • regulation of epithelial cell proliferation • prostate gland morphogenesis • negative regulation of endopeptidase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5268	n/a
Ensembl	ENSG00000206075	n/a
UniProt	P36952	n/a
RefSeq (mRNA)	NM_002639	n/a
RefSeq (protein)	NP_002630	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SERPINB5 yw SERPINB5 a elwir hefyd yn Serpin B5 a Serpin family B member 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 18, band 18q21.33.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SERPINB5.

• PI5
• maspin

• "Maspin suppresses growth, proliferation and invasion in cutaneous squamous cell carcinoma cells. ". Oncol Rep. 2017. PMID 28405681.
• "Combinations of SERPINB5 gene polymorphisms and environmental factors are associated with oral cancer risks. ". PLoS One. 2017. PMID 28339463.
• "Maspin inhibits macrophage phagocytosis and enhances inflammatory cytokine production via activation of NF-κB signaling. ". Mol Immunol. 2017. PMID 28064070.
• "Expression of maspin in invasive fungal rhinosinusitis. ". J Laryngol Otol. 2017. PMID 28031066.
• "Identification of novel peptide motifs in the serpin maspin that affect vascular smooth muscle cell function.". Biochim Biophys Acta. 2017. PMID 27888098.