SENP8

1XT9, 2BKQ, 2BKR

SENP8
SENP8
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauSENP8, DEN1, NEDP1, PRSC2, SUMO/sentrin peptidase family member, NEDD8 specific, SUMO peptidase family member, NEDD8 specific
Dynodwyr allanolOMIM: 608659 HomoloGene: 14084 GeneCards: SENP8
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

123228

n/a

Ensembl

ENSG00000166192

n/a

UniProt

Q96LD8

n/a

RefSeq (mRNA)

NM_001166340
NM_001172109
NM_001172110
NM_001172111
NM_145204

n/a

RefSeq (protein)

NP_001159812
NP_001165580
NP_001165581
NP_001165582
NP_660205

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn SENP8 yw SENP8 a elwir hefyd yn Sentrin-specific protease 8 a SUMO/sentrin peptidase family member, NEDD8 specific (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q23.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn SENP8.

  • DEN1
  • NEDP1
  • PRSC2

Llyfryddiaeth

  • "A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity. ". Anal Biochem. 2009. PMID 19328766.
  • "Structural basis of NEDD8 ubiquitin discrimination by the deNEDDylating enzyme NEDP1. ". EMBO J. 2005. PMID 15775960.
  • "The molecular determinants of NEDD8 specific recognition by human SENP8. ". PLoS One. 2011. PMID 22110750.
  • "DeSUMOylating enzymes--SENPs. ". IUBMB Life. 2008. PMID 18666185.
  • "Central role for endothelial human deneddylase-1/SENP8 in fine-tuning the vascular inflammatory response.". J Immunol. 2013. PMID 23209320.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ SENP8 - Cronfa NCBI

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