RGS1

RGS1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2BV1, 2GTP
Dynodwyr
Cyfenwau	RGS1, 1R20, BL34, HEL-S-87, IER1, IR20, regulator of G-protein signaling 1, regulator of G protein signaling 1
Dynodwyr allanol	OMIM: 600323 HomoloGene: 2191 GeneCards: RGS1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • G-protein alpha-subunit binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity • calmodulin binding • GO:0006184 GTPase activity Cydrannau o'r gell • extrinsic component of cytoplasmic side of plasma membrane • cytosol • cellbilen • bilen • cytoplasm Prosesau biolegol • G protein-coupled receptor signaling pathway • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • negative regulation of signal transduction • leukotriene signaling pathway • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • regulation of G protein-coupled receptor signaling pathway • GO:0072468 signal transduction • response to bacterium Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5996	n/a
Ensembl	ENSG00000090104	n/a
UniProt	Q08116	n/a
RefSeq (mRNA)	NM_002922	n/a
RefSeq (protein)	NP_002913	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RGS1 yw RGS1 a elwir hefyd yn Regulator of G protein signaling 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q31.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RGS1.

• "Genetic association between RGS1 and internalizing disorders. ". Psychiatr Genet. 2013. PMID 23324853.
• "Identification of RGS1 as a candidate biomarker for undifferentiated spondylarthritis by genome-wide expression profiling and real-time polymerase chain reaction. ". Arthritis Rheum. 2009. PMID 19877080.
• "Clinicopathological characteristics and genomic profile of primary sinonasal tract diffuse large B cell lymphoma (DLBCL) reveals gain at 1q31 and RGS1 encoding protein; high RGS1 immunohistochemical expression associates with poor overall survival in DLBCL not otherwise specified (NOS). ". Histopathology. 2017. PMID 27775850.
• "RGS1 expression is associated with poor prognosis in multiple myeloma. ". J Clin Pathol. 2017. PMID 27445341.
• "Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue.". PLoS One. 2015. PMID 26222051.