RBP1

5HA1, 5HBS, 5H8T, 5H9A

RBP1
RBP1
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauRBP1, CRABP-I, CRBP, CCRBPI, RBPC, retinol binding protein 1
Dynodwyr allanolOMIM: 180260 HomoloGene: 2175 GeneCards: RBP1
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

5947

n/a

Ensembl

ENSG00000114115

n/a

UniProt

P09455

n/a

RefSeq (mRNA)

NM_002899
NM_001130992
NM_001130993
NM_001365940

n/a

RefSeq (protein)

NP_001124464
NP_001124465
NP_002890
NP_001352869

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RBP1 yw RBP1 a elwir hefyd yn Retinol binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q23.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RBP1.

  • CRBP
  • RBPC
  • CRBP1
  • CRBPI
  • CRABP-I

Llyfryddiaeth

  • "Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins. ". Biomed Res Int. 2015. PMID 25879031.
  • "CRBP-1 expression in ovarian cancer: a potential therapeutic target. ". Anticancer Res. 2014. PMID 24982334.
  • "Comprehensive molecular exploration identified promoter DNA methylation of the CRBP1 gene as a determinant of radiation sensitivity in rectal cancer. ". Br J Cancer. 2017. PMID 28291773.
  • "Structural and molecular determinants affecting the interaction of retinol with human CRBP1. ". J Struct Biol. 2017. PMID 28057518.
  • "Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures.". J Biol Chem. 2016. PMID 26900151.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ RBP1 - Cronfa NCBI

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