RASSF8

2CS4

RASSF8
RASSF8
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauRASSF8, C12orf2, HOJ1, Ras association domain family member 8
Dynodwyr allanolOMIM: 608231 HomoloGene: 5219 GeneCards: RASSF8
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

11228

n/a

Ensembl

ENSG00000123094

n/a

UniProt

Q8NHQ8

n/a

RefSeq (mRNA)

NM_001164746
NM_001164747
NM_001164748
NM_007211

n/a

RefSeq (protein)

NP_001158218
NP_001158219
NP_001158220
NP_009142

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn RASSF8 yw RASSF8 a elwir hefyd yn Ras association domain-containing protein 8 a Ras association domain family member 8 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12p12.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn RASSF8.

  • HOJ1
  • C12orf2

Llyfryddiaeth

  • "Physical map of a 1.5 mb region on 12p11.2 harbouring a synpolydactyly associated chromosomal breakpoint. ". Eur J Hum Genet. 2000. PMID 10951517.
  • "Hypoxia-inducible microRNA-224 promotes the cell growth, migration and invasion by directly targeting RASSF8 in gastric cancer. ". Mol Cancer. 2017. PMID 28173803.
  • "RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma. ". Oncotarget. 2015. PMID 26439687.
  • "RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb. ". Oncotarget. 2015. PMID 26334503.
  • "Identification of RASSF8 as a candidate lung tumor suppressor gene.". Oncogene. 2006. PMID 16462760.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ RASSF8 - Cronfa NCBI

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