PSTPIP1

PSTPIP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DIL
Dynodwyr
Cyfenwau	PSTPIP1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP, proline-serine-threonine phosphatase interacting protein 1
Dynodwyr allanol	OMIM: 606347 HomoloGene: 37867 GeneCards: PSTPIP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • identical protein binding • cytoskeletal protein binding • actin filament binding Cydrannau o'r gell • cytoplasm • perinuclear region of cytoplasm • cytosol • cellbilen • uropod • cleavage furrow • cell projection • Cytosgerbwd • bilen • lamellipodium • Microffilament Prosesau biolegol • cell adhesion • inflammatory response • endocytosis • GO:0072468 signal transduction • proses y system imiwnedd • innate immune response • actin filament polymerization • cell migration Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9051	n/a
Ensembl	ENSG00000140368	n/a
UniProt	O43586	n/a
RefSeq (mRNA)	NM_003978 NM_001321135 NM_001321136 NM_001321137	n/a
RefSeq (protein)	NP_001308064 NP_001308065 NP_001308066 NP_003969	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSTPIP1 yw PSTPIP1 a elwir hefyd yn Proline-serine-threonine phosphatase-interacting protein 1 a Proline-serine-threonine phosphatase interacting protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 15, band 15q24.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSTPIP1.

• "Identification of novel mutations in CD2BP1 gene in clinically proven rheumatoid arthritis patients of south India. ". Eur J Med Genet. 2016. PMID 27184502.
• "Pyrin-PSTPIP1 colocalises at the leading edge during cell migration. ". Cell Biol Int. 2015. PMID 26179737.
• "HPIP silencing inhibits TGF-β1-induced EMT in lung cancer cells. ". Int J Mol Med. 2017. PMID 28075456.
• "HPIP promotes epithelial-mesenchymal transition and cisplatin resistance in ovarian cancer cells through PI3K/AKT pathway activation. ". Cell Oncol (Dordr). 2017. PMID 28039608.
• "Knockdown of HPIP Inhibits the Proliferation and Invasion of Head-and-Neck Squamous Cell Carcinoma Cells by Regulating PI3K/Akt Signaling Pathway.". Oncol Res. 2016. PMID 27458096.