PSMB6

PSMB6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4R3O, 4R67, 5A0Q
Dynodwyr
Cyfenwau	PSMB6, DELTA, LMPY, proteasome subunit beta 6, Y, proteasome 20S subunit beta 6
Dynodwyr allanol	OMIM: 600307 HomoloGene: 2092 GeneCards: PSMB6
EC number	3.4.25.1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • endopeptidase activity • GO:0070122 peptidase activity • threonine-type endopeptidase activity • hydrolase activity • cadherin binding Cydrannau o'r gell • nucleoplasm • proteasome complex • extracellular exosome • cnewyllyn cell • proteasome core complex • cytoplasm • cytosol • proteasome core complex, beta-subunit complex Prosesau biolegol • regulation of cellular amino acid metabolic process • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent • regulation of mRNA stability • positive regulation of canonical Wnt signaling pathway • protein polyubiquitination • stimulatory C-type lectin receptor signaling pathway • tumor necrosis factor-mediated signaling pathway • MAPK cascade • proteolysis • Fc-epsilon receptor signaling pathway • NIK/NF-kappaB signaling • anaphase-promoting complex-dependent catabolic process • proteolysis involved in cellular protein catabolic process • T cell receptor signaling pathway • negative regulation of canonical Wnt signaling pathway • proteasome-mediated ubiquitin-dependent protein catabolic process • GO:0022415 viral process • Wnt signaling pathway, planar cell polarity pathway • negative regulation of G2/M transition of mitotic cell cycle • protein deubiquitination • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process • transmembrane transport • regulation of transcription from RNA polymerase II promoter in response to hypoxia • post-translational protein modification • regulation of hematopoietic stem cell differentiation • proteasomal protein catabolic process • proteasomal ubiquitin-independent protein catabolic process • interleukin-1-mediated signaling pathway • regulation of mitotic cell cycle phase transition Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5694	n/a
Ensembl	ENSG00000142507	n/a
UniProt	P28072	n/a
RefSeq (mRNA)	NM_002798 NM_001270481	n/a
RefSeq (protein)	NP_001257410 NP_002789	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMB6 yw PSMB6 a elwir hefyd yn Proteasome subunit beta 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 17, band 17p13.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMB6.

• Y
• LMPY
• DELTA

• "Subcellular recruitment of fibrillarin to nucleoplasmic proteasomes: implications for processing of a nucleolar autoantigen. ". Mol Biol Cell. 2002. PMID 12388758.
• "Relationships among the subunits of the high molecular weight proteinase, macropain (proteasome). ". Biochim Biophys Acta. 1990. PMID 2306472.
• "Evaluation of Zinc-α-2-Glycoprotein and Proteasome Subunit β-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology. ". Appl Immunohistochem Mol Morphol. 2010. PMID 20661134.
• "cDNA cloning and interferon gamma down-regulation of proteasomal subunits X and Y. ". Science. 1994. PMID 8066462.
• "Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins.". Curr Biol. 1994. PMID 7820546.