PSMA2

PSMA2
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	4R3O, 4R67, 5A0Q
Dynodwyr
Cyfenwau	PSMA2, HC3, MU, PMSA2, PSC2, proteasome subunit alpha 2, proteasome 20S subunit alpha 2
Dynodwyr allanol	OMIM: 176842 HomoloGene: 2081 GeneCards: PSMA2
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• endopeptidase activity; • GO:0070122 peptidase activity; • GO:0001948, GO:0016582 protein binding; • threonine-type endopeptidase activity; • hydrolase activity;
Cydrannau o'r gell	• cytoplasm; • cytosol; • nucleoplasm; • proteasome complex; • extracellular exosome; • cnewyllyn cell; • proteasome core complex; • extracellular region; • secretory granule lumen; • ficolin-1-rich granule lumen; • proteasome core complex, alpha-subunit complex; • P-body;
Prosesau biolegol	• regulation of cellular amino acid metabolic process; • antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; • regulation of mRNA stability; • ubiquitin-dependent protein catabolic process; • positive regulation of canonical Wnt signaling pathway; • response to virus; • protein polyubiquitination; • stimulatory C-type lectin receptor signaling pathway; • tumor necrosis factor-mediated signaling pathway; • proteolysis; • MAPK cascade; • Fc-epsilon receptor signaling pathway; • NIK/NF-kappaB signaling; • anaphase-promoting complex-dependent catabolic process; • proteolysis involved in cellular protein catabolic process; • T cell receptor signaling pathway; • negative regulation of canonical Wnt signaling pathway; • proteasome-mediated ubiquitin-dependent protein catabolic process; • Wnt signaling pathway, planar cell polarity pathway; • negative regulation of G2/M transition of mitotic cell cycle; • protein deubiquitination; • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; • neutrophil degranulation; • transmembrane transport; • regulation of transcription from RNA polymerase II promoter in response to hypoxia; • post-translational protein modification; • regulation of hematopoietic stem cell differentiation; • proteasomal protein catabolic process; • proteasomal ubiquitin-independent protein catabolic process; • interleukin-1-mediated signaling pathway; • regulation of mitotic cell cycle phase transition;
	Sources:Amigo / QuickGO
Orthologau
	5683
	n/a
	ENSG00000106588
	n/a
	P25787
	n/a
	NM_002787
	n/a
	NP_002778
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PSMA2 yw PSMA2 a elwir hefyd yn Proteasome subunit alpha 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p14.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PSMA2.

MU
HC3
PSC2
PMSA2

Llyfryddiaeth

"Functional analysis of eukaryotic 20S proteasome nuclear localization signal. ". Exp Cell Res. 1996. PMID 8635518.
"Isolation and characterization of alpha-type HC3 and beta-type HC5 subunit genes of human proteasomes. ". J Mol Biol. 1994. PMID 7966316.
"[Expression of genes psma6 and slc25a4 in patients with acute monocytic leukemia]. ". Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009. PMID 19840444.
"Mechanism of direct degradation of IkappaBalpha by 20S proteasome. ". FEBS Lett. 2005. PMID 16098527.
"The ubiquitin-associated domain of hPLIC-2 interacts with the proteasome.". Mol Biol Cell. 2003. PMID 12972570.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] PSMA2 - Cronfa NCBI

[1]

[2]

PSMA2

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

Content Disclaimer