PRG4

10216

PRG4
PRG4
Dynodwyr
CyfenwauPRG4, CACP, HAPO, JCAP, MSF, SZP, bG174L6.2, proteoglycan 4
Dynodwyr allanolOMIM: 604283 HomoloGene: 130465 GeneCards: PRG4
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

10216

n/a

Ensembl

ENSG00000116690

n/a

UniProt

Q92954

n/a

RefSeq (mRNA)

NM_005807
NM_001127708
NM_001127709
NM_001127710
NM_001303232

n/a

RefSeq (protein)

NP_001121180
NP_001121181
NP_001121182
NP_001290161
NP_005798

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PRG4 yw PRG4 a elwir hefyd yn Proteoglycan 4 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q31.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PRG4.

  • MSF
  • SZP
  • CACP
  • HAPO
  • JCAP

Llyfryddiaeth

  • "Does intra-articular fracture change the lubricant content of synovial fluid?". J Orthop Surg Res. 2015. PMID 26037740.
  • "Biosynthesis of collagen I, II, RUNX2 and lubricin at different time points of chondrogenic differentiation in a 3D in vitro model of human mesenchymal stem cells derived from adipose tissue. ". Acta Histochem. 2014. PMID 25307495.
  • "PRG4 expression in myxoid liposarcoma maintains tumor cell growth through suppression of an antitumor cytokine IL-24. ". Biochem Biophys Res Commun. 2017. PMID 28192118.
  • "Implications of trauma and subsequent articulation on the release of Proteoglycan-4 and tissue response in adult human ankle cartilage. ". J Orthop Res. 2017. PMID 27551813.
  • "Abundant lubricin expression suggests a link between synoviocytes, synovial tumors, and myxomas.". Histol Histopathol. 2016. PMID 26924731.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ PRG4 - Cronfa NCBI

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