PREP

3DDU

PREP
PREP
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauPREP, PE, PEP, prolyl endopeptidase
Dynodwyr allanolOMIM: 600400 HomoloGene: 2042 GeneCards: PREP
EC number3.4.21.26
Patrwm RNA pattern


Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

5550

n/a

Ensembl

ENSG00000085377

n/a

UniProt

P48147

n/a

RefSeq (mRNA)

NM_002726

n/a

RefSeq (protein)

NP_002717

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PREP yw PREP a elwir hefyd yn Prolyl endopeptidase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q21.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PREP.

  • PE
  • PEP

Llyfryddiaeth

  • "Ligand-induced conformational changes in prolyl oligopeptidase: a kinetic approach. ". Protein Eng Des Sel. 2017. PMID 28062644.
  • "Prolyl Oligopeptidase Inhibition Attenuates Steatosis in the L02 Human Liver Cell Line. ". PLoS One. 2016. PMID 27760195.
  • "The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients. ". J Neuroinflammation. 2015. PMID 26420028.
  • "Mechanism of oxidative inactivation of human presequence protease by hydrogen peroxide. ". Free Radic Biol Med. 2014. PMID 25236746.
  • "Molecular basis of substrate recognition and degradation by human presequence protease.". Structure. 2014. PMID 24931469.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ PREP - Cronfa NCBI

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