PPIL1

PPIL1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XWN, 2K7N, 2X7K
Dynodwyr
Cyfenwau	PPIL1, CYPL1, PPIase, hCyPX, CGI-124, peptidylprolyl isomerase like 1, PCH14
Dynodwyr allanol	OMIM: 601301 HomoloGene: 9367 GeneCards: PPIL1
EC number	5.2.1.8
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • isomerase activity • GO:0001948, GO:0016582 protein binding • disordered domain specific binding • peptidyl-prolyl cis-trans isomerase activity • cyclosporin A binding Cydrannau o'r gell • catalytic step 2 spliceosome • spliceosomal complex • nucleoplasm • cnewyllyn cell • U2-type catalytic step 2 spliceosome Prosesau biolegol • mRNA processing • protein folding • RNA splicing • mRNA splicing, via spliceosome • protein peptidyl-prolyl isomerization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51645	n/a
Ensembl	ENSG00000137168	n/a
UniProt	Q9Y3C6	n/a
RefSeq (mRNA)	NM_016059	n/a
RefSeq (protein)	NP_057143	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PPIL1 yw PPIL1 a elwir hefyd yn Peptidylprolyl isomerase like 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PPIL1.

• "The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein. ". PLoS One. 2010. PMID 20368803.
• "Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP. ". J Biol Chem. 2006. PMID 16595688.
• "Backbone and side chain assignments of human Peptidylprolyl Isomerase Like 1 (hPPIL1). ". J Biomol NMR. 2005. PMID 15772761.
• "Reassignment of peptidyl prolyl isomerase-like 1 gene (PPIL1) to human chromosome region 6p21.1 by radiation hybrid mapping and fluorescence in situ hybridization. ". Cytogenet Cell Genet. 1998. PMID 10072585.
• "Cloning, expression and chromosomal mapping of a novel cyclophilin-related gene (PPIL1) from human fetal brain.". Cytogenet Cell Genet. 1996. PMID 8978786.