POLR2H

POLR2H
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2F3I, 5FLM, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Dynodwyr
Cyfenwau	POLR2H, RPABC3, RPB17, RPB8, polymerase (RNA) II subunit H, RNA polymerase II subunit H, RNA polymerase II, I and III subunit H
Dynodwyr allanol	OMIM: 606023 HomoloGene: 4540 GeneCards: POLR2H
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• DNA-directed 5'-3' RNA polymerase activity; • DNA binding; • RNA polymerase I activity; • RNA polymerase II activity; • RNA polymerase III activity; • single-stranded DNA binding;
Cydrannau o'r gell	• nucleolus; • RNA polymerase II, core complex; • nucleoplasm; • cytosol; • cnewyllyn cell; • RNA polymerase III complex; • RNA polymerase I complex; • protein-DNA complex;
Prosesau biolegol	• 7-methylguanosine mRNA capping; • transcription elongation from RNA polymerase II promoter; • transcription initiation from RNA polymerase I promoter; • mRNA splicing, via spliceosome; • epigenetic maintenance of chromatin in transcription-competent conformation; • transcription-coupled nucleotide-excision repair; • termination of RNA polymerase I transcription; • transcription initiation from RNA polymerase II promoter; • transcription by RNA polymerase II; • snRNA transcription by RNA polymerase II; • fibroblast growth factor receptor signaling pathway; • transcription by RNA polymerase III; • RNA metabolic process; • GO:1905616 regulation of gene silencing by miRNA; • transcription, DNA-templated; • GO:0001183 transcription elongation from RNA polymerase I promoter; • positive regulation of type I interferon production; • somatic stem cell population maintenance; • positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologau
	5437
	n/a
	ENSG00000163882
	n/a
	P52434
	n/a
NM_001278698; NM_001278699; NM_001278700; NM_001278714; NM_001278715;
	NM_006232; NM_001346879
	n/a
NP_001265627; NP_001265628; NP_001265629; NP_001265643; NP_001265644;
	NP_001333808; NP_006223
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn POLR2H yw POLR2H a elwir hefyd yn RNA polymerase II subunit H (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q27.1.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POLR2H.

RPB8
RPB17
RPABC3

Llyfryddiaeth

"Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. ". Mol Cell Biol. 1995. PMID 7651387.
"Intrinsic disorder drives N-terminal ubiquitination by Ube2w. ". Nat Chem Biol. 2015. PMID 25436519.
"Characterization of RNA polymerase type II from human term placenta. ". J Cell Physiol. 1986. PMID 3754875.
"Structural, biochemical, and dynamic characterizations of the hRPB8 subunit of human RNA polymerases. ". J Biol Chem. 2006. PMID 16632472.
"Six human RNA polymerase subunits functionally substitute for their yeast counterparts.". Mol Cell Biol. 1995. PMID 8524256.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] POLR2H - Cronfa NCBI

[1]

[2]

POLR2H

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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