POLR2G

POLR2G
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2C35, 5FLM, 5IY9, 5IYA, 5IYC, 5IYB, 5IY7, 5IY8, 5IYD, 5IY6
Dynodwyr
Cyfenwau	POLR2G, RPB19, RPB7, hRPB19, hsRPB7, polymerase (RNA) II subunit G, RNA polymerase II subunit G
Dynodwyr allanol	OMIM: 602013 HomoloGene: 2019 GeneCards: POLR2G
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA-directed 5'-3' RNA polymerase activity • single-stranded DNA binding • single-stranded RNA binding • RNA binding • nucleic acid binding • translation initiation factor binding Cydrannau o'r gell • P-body • nucleoplasm • RNA polymerase II, core complex • cnewyllyn cell Prosesau biolegol • mRNA splicing, via spliceosome • positive regulation of nuclear-transcribed mRNA poly(A) tail shortening • transcription elongation from RNA polymerase II promoter • 7-methylguanosine mRNA capping • transcription by RNA polymerase II • transcription-coupled nucleotide-excision repair • transcription initiation from RNA polymerase II promoter • positive regulation of translational initiation • nuclear-transcribed mRNA catabolic process, exonucleolytic • GO:0097285 apoptotic process • snRNA transcription by RNA polymerase II • fibroblast growth factor receptor signaling pathway • RNA metabolic process • GO:1905616 regulation of gene silencing by miRNA • transcription, DNA-templated • somatic stem cell population maintenance • positive regulation of viral transcription Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	5436	n/a
Ensembl	ENSG00000168002	n/a
UniProt	P62487	n/a
RefSeq (mRNA)	NM_002696	n/a
RefSeq (protein)	NP_002687	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn POLR2G yw POLR2G a elwir hefyd yn RNA polymerase II subunit G (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 11, band 11q12.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POLR2G.

• "Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II. ". Nucleic Acids Res. 2005. PMID 16282592.
• "Identification of the RNA polymerase II subunit hsRPB7 as a novel target of the von Hippel-Lindau protein. ". EMBO J. 2003. PMID 12912922.
• "RNA emerging from the active site of RNA polymerase II interacts with the Rpb7 subunit. ". Nat Struct Mol Biol. 2006. PMID 16327806.
• "The RNA Pol II sub-complex hsRpb4/7 is required for viability of multiple human cell lines. ". Protein Cell. 2012. PMID 23073835.
• "Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription.". Biochem J. 2008. PMID 17848138.