POLR2D

POLR2D
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	2C35, 5IYD, 5IY8, 5IYC, 5IY6, 5IY7, 5IYA, 5IY9, 5IYB
Dynodwyr
Cyfenwau	POLR2D, HSRBP4, HSRPB4, RBP4, RPB16, RNA polymerase II subunit B4, polymerase (RNA) II subunit D, RNA polymerase II subunit D, RPB4
Dynodwyr allanol	OMIM: 606017 HomoloGene: 37968 GeneCards: POLR2D
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• nucleotide binding; • DNA-directed 5'-3' RNA polymerase activity; • single-stranded DNA binding; • catalytic activity; • single-stranded RNA binding; • translation initiation factor binding;
Cydrannau o'r gell	• P-body; • RNA polymerase II, core complex; • cnewyllyn cell; • nucleoplasm; • cytosol; • nuclear speck; • nuclear DNA-directed RNA polymerase complex; • RNA polymerase complex;
Prosesau biolegol	• mRNA splicing, via spliceosome; • recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex; • transcription elongation from RNA polymerase II promoter; • 7-methylguanosine mRNA capping; • transcription by RNA polymerase II; • nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; • metaboledd celloedd; • transcription-coupled nucleotide-excision repair; • transcription initiation from RNA polymerase II promoter; • positive regulation of translational initiation; • mRNA export from nucleus in response to heat stress; • fibroblast growth factor receptor signaling pathway; • snRNA transcription by RNA polymerase II; • RNA metabolic process; • GO:1905616 regulation of gene silencing by miRNA; • DNA-templated transcription, initiation; • transcription, DNA-templated; • somatic stem cell population maintenance; • positive regulation of viral transcription;
	Sources:Amigo / QuickGO
Orthologau
	5433
	n/a
	ENSG00000144231
	n/a
	O15514
	n/a
	NM_004805
	n/a
	NP_004796
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn POLR2D yw POLR2D a elwir hefyd yn RNA polymerase II subunit D (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q14.3.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn POLR2D.

RBP4
RPB16
HSRBP4
HSRPB4

Llyfryddiaeth

"SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. ". Nature. 2016. PMID 26700805.
"Inhibition of HIV-1 virus replication using small soluble Tat peptides. ". Virology. 2006. PMID 16289656.
"Crystal structure and RNA binding of the Rpb4/Rpb7 subunits of human RNA polymerase II. ". Nucleic Acids Res. 2005. PMID 16282592.
"Analysis of the interaction of the novel RNA polymerase II (pol II) subunit hsRPB4 with its partner hsRPB7 and with pol II. ". Mol Cell Biol. 1998. PMID 9528765.
"Interactions between the full complement of human RNA polymerase II subunits.". FEBS Lett. 1999. PMID 10567706.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] POLR2D - Cronfa NCBI

[1]

[2]

POLR2D

Cyfystyron

Llyfryddiaeth

Cyfeiriadau

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