PLEKHA5

PLEKHA5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DKP
Dynodwyr
Cyfenwau	PLEKHA5, PEPP-2, PEPP2, pleckstrin homology domain containing A5
Dynodwyr allanol	OMIM: 607770 HomoloGene: 10377 GeneCards: PLEKHA5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatidylinositol-4-phosphate binding • phosphatidylinositol-5-phosphate binding • GO:0001948, GO:0016582 protein binding • phosphatidylinositol-3-phosphate binding • phosphatidylinositol-3,5-bisphosphate binding Cydrannau o'r gell • bilen • nucleoplasm • cytoplasm • cytosol • GO:0097483, GO:0097481 postsynaptic density • glutamatergic synapse Prosesau biolegol • reproductive system development • GO:0022610 proses fiolegol Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54477	n/a
Ensembl	ENSG00000052126	n/a
UniProt	Q9HAU0	n/a
RefSeq (mRNA)	NM_001143821 NM_001190860 NM_001256470 NM_001256787 NM_019012	n/a
RefSeq (protein)	NP_001137293 NP_001177789 NP_001243399 NP_001243716 NP_061885 NP_001137293.2	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PLEKHA5 yw PLEKHA5 a elwir hefyd yn Pleckstrin homology domain containing, family A member 5, isoform CRA_a a Pleckstrin homology domain containing A5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12p12.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PLEKHA5.

• PEPP2
• PEPP-2

• "Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. ". Biochem J. 2000. PMID 11001876.
• "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. ". Mol Cell Proteomics. 2005. PMID 15951569.
• "PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis. ". Clin Cancer Res. 2015. PMID 25316811.
• "Identification and characterization of splicing variants of PLEKHA5 (Plekha5) during brain development. ". Gene. 2012. PMID 22037487.
• "Identification of differentially expressed genes in human melanoma cells with acquired resistance to various antineoplastic drugs.". Int J Cancer. 2000. PMID 11058868.