PITPNB

PITPNB
Dynodwyr
Cyfenwau	PITPNB, PI-TP-beta, PtdInsTP, VIB1B, phosphatidylinositol transfer protein beta
Dynodwyr allanol	OMIM: 606876 HomoloGene: 4533 GeneCards: PITPNB
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipid binding • phosphatidylcholine transporter activity • phosphatidylinositol transfer activity • phosphatidylcholine binding • phosphatidylinositol binding • phospholipid transporter activity Cydrannau o'r gell • cytoplasm • Golgi membrane • Golgi apparatus • endoplasmic reticulum membrane • intracellular anatomical structure Prosesau biolegol • lipid metabolism • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum • nucleus organization • phospholipid transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23760	n/a
Ensembl	ENSG00000180957	n/a
UniProt	P48739	n/a
RefSeq (mRNA)	NM_001284277 NM_001284278 NM_012399	n/a
RefSeq (protein)	NP_001271206 NP_001271207 NP_036531	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PITPNB yw PITPNB a elwir hefyd yn Phosphatidylinositol transfer protein beta (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 22, band 22q12.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PITPNB.

• VIB1B
• PtdInsTP
• PI-TP-beta

• "Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein beta lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment. ". Biochem J. 2006. PMID 16780419.
• "Cloning and expression of human cDNA encoding phosphatidylinositol transfer protein beta. ". Biochim Biophys Acta. 1995. PMID 8541325.
• "Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum. ". J Cell Sci. 2010. PMID 20332109.
• "Comparative proteomic analysis of peripheral blood mononuclear cells from atopic dermatitis patients and healthy donors. ". BMB Rep. 2008. PMID 18755076.
• "Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin.". Biochem J. 2002. PMID 12023904.