PFN2

1D1J

PFN2
PFN2
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauPFN2, D3S1319E, PFL, profilin 2
Dynodwyr allanolOMIM: 176590 HomoloGene: 1974 GeneCards: PFN2
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez

5217

n/a

Ensembl

ENSG00000070087

n/a

UniProt

P35080

n/a

RefSeq (mRNA)

NM_053024
NM_002628

n/a

RefSeq (protein)

NP_002619
NP_444252

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PFN2 yw PFN2 a elwir hefyd yn Profilin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q25.1.[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PFN2.

  • PFL
  • D3S1319E

Llyfryddiaeth

  • "Decreased expression of profilin 2 in oral squamous cell carcinoma and its clinicopathological implications. ". Oncol Rep. 2011. PMID 21725608.
  • "Cloning and expression of a novel human profilin variant, profilin II. ". FEBS Lett. 1993. PMID 8365484.
  • "PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma. ". J Transl Med. 2016. PMID 27188458.
  • "Epigenetic regulation of Smad2 and Smad3 by profilin-2 promotes lung cancer growth and metastasis. ". Nat Commun. 2015. PMID 26354229.
  • "Profilin 2 promotes migration, invasion, and stemness of HT29 human colorectal cancer stem cells.". Biosci Biotechnol Biochem. 2015. PMID 25964982.

Cyfeiriadau

  1. ↑ "Human PubMed Reference:".
  2. ↑ PFN2 - Cronfa NCBI

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.