PDLIM3

PDLIM3
Dynodwyr
Cyfenwau	PDLIM3, ALP, PDZ and LIM domain 3
Dynodwyr allanol	OMIM: 605889 HomoloGene: 8710 GeneCards: PDLIM3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • metal ion binding • cytoskeletal protein binding • structural constituent of muscle • actin binding • muscle alpha-actinin binding Cydrannau o'r gell • Z discdkac • cytoplasm • actin cytoskeleton • stress fiber • filamentous actin Prosesau biolegol • development of the heart • actin filament organization • actin cytoskeleton organization • muscle structure development Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	27295	n/a
Ensembl	ENSG00000154553	n/a
UniProt	Q53GG5	n/a
RefSeq (mRNA)	NM_001114107 NM_001257962 NM_001257963 NM_014476	n/a
RefSeq (protein)	NP_001107579 NP_001244891 NP_001244892 NP_055291	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn PDLIM3 yw PDLIM3 a elwir hefyd yn PDZ and LIM domain 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q35.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn PDLIM3.

• ALP

• "Analysis of the Z-disc genes PDLIM3 and MYPN in patients with hypertrophic cardiomyopathy. ". Int J Cardiol. 2010. PMID 20801532.
• "Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy. ". Mol Genet Metab. 2007. PMID 17254821.
• "Alternative splicing of PDLIM3/ALP, for α-actinin-associated LIM protein 3, is aberrant in persons with myotonic dystrophy. ". Biochem Biophys Res Commun. 2011. PMID 21549096.
• "Characterization of lobulated fibers in limb girdle muscular dystrophy type 2A by gene expression profiling. ". Neurosci Res. 2007. PMID 17258832.
• "Exclusion of muscle specific actinin-associated LIM protein (ALP) gene from 4q35 facioscapulohumeral muscular dystrophy (FSHD) candidate genes.". Neuromuscul Disord. 1999. PMID 10063829.